For patients with lupus erythematosus rash, the preferred oral medication is hydroxychloroquine, and the dose chosen is 0.2-0.4g daily, which can be reduced to half dose after the condition improves, sometimes 0.2g per week can control the condition, depending on the patient’s tolerance and condition. Since hydroxychloroquine can cause eye lesions, regular fundus examination should be done, usually once every 3 months. For topical medications, you can choose glucocorticoids or non-hormonal drugs. For common hormonal drugs, you can choose Eloson and Denide for the face, and medium to strong tretinoin and halometasone ointment for other parts. Non-hormonal calcium-regulated phosphatase inhibitors, which are now also widely used in clinical practice, mainly include tacrolimus ointment and pimecrolimus ointment. Meanwhile, patients with lupus erythematosus must avoid sun exposure, especially those who are sensitive to sunlight should pay special attention and use sunscreen, sunshade or wear a wide-brimmed hat when going out.