The usage of insulin for pregnant women is not much different from that of the general population, with subcutaneous injections being the mainstay. If you use preprandial short-acting insulin, it is recommended to inject the outer side of the upper arm, with the outer 1/3 of the outer arm as the injection zone. For intermediate-acting insulin and long-acting insulin, you can choose to inject insulin into the outer part of the thigh, which is more favorable for insulin absorption. Injections are given under the skin, not into the muscle. If the drug is injected into the muscle, it will be absorbed too quickly, which will easily lead to hypoglycemia. Try to rotate the injection in different parts of the body as much as possible, if you always inject in one part of the body, it is easy to form a hard knot. In the second trimester due to the increase of insulin resistance in the second trimester, pregnant women’s blood sugar will rise significantly, so the dose of insulin used in the second trimester of pregnancy will be adjusted, it is recommended that regular monitoring of blood glucose, under the guidance of the physician to develop a program. Each person has a different constitution and is sensitive to insulin, so each diabetic pregnant woman should draw up a specific treatment plan and gradually increase the insulin dosage to prevent hypoglycemia. Severe hypoglycemia may lead to fetal risk. It has been reported in the literature that the probability of intrauterine fetal death and fetal anomalies in pregnant women with hypoglycemia is four times higher than that in pregnant women with normal blood glucose. Insulin injection for pregnant women with diabetes does not usually have an effect on fetal development, but it should be noted that there may be a hypoglycemic reaction during the first 1-2 injections, so be careful to prepare sugar cubes and take them as soon as possible once there is a hypoglycemic reaction, and you can start injecting slowly with a small dosage and gradually adjust the treatment.