Colorectal cancer combined with liver metastasis is advanced stage, and the survival of patients varies from person to person. Some studies claim that the 1-, 3- and 5-year survival rates of patients with colorectal cancer combined with liver metastasis are 77.7%, 29.1% and 12.8% in order. Colorectal cancer is a malignant tumor originating from colorectal cancer, which is one of the common malignant tumors in the digestive system and has a poor prognosis. Liver is the most important target organ for hematogenous metastasis of colorectal cancer, and liver metastasis of colorectal cancer is one of the focuses and difficulties in colorectal cancer treatment. Some studies claim that about 15%~25% of colorectal cancer patients are combined with liver metastasis at the time of diagnosis, and another 15%~25% of patients will develop liver metastasis after radical resection of colorectal cancer primary foci, and the vast majority of them (80%~90%) are unable to obtain radical resection of liver metastasis initially. Liver metastasis is also the most important cause of death in colorectal cancer patients. The median survival of untreated liver metastasis patients is only 6.9 months, and the 5-year survival rate of unresectable patients is less than 5%, while the median survival of patients with liver metastasis that can be completely resected [or can reach the status of “no evidence of disease”] is 35 months, and the 5-year survival rate can be up to 30%~57%. Early detection, early diagnosis and early treatment are the keys to prolonging the survival of patients. It is recommended to go to a regular hospital and follow the doctor’s instructions to avoid delaying the disease.