Diarrhea in adults is seen in intestinal bacterial infections. A temperature above 38°C indicates a more serious infection and should be treated with antibiotics. Antibiotics can be selected from levofloxacin hydrochloride and third-generation cephalosporins, which can be ingested orally or administered intravenously. When the body temperature is lower than 38.5℃, it is not recommended to give cooling drugs, and physical cooling can be given by wiping the forehead, temples, neck, armpits, wrists, elbows and thigh roots with warm water. If the patient’s body temperature exceeds 38.5℃, blood culture is recommended, and medication is also given to lower the temperature, usually by compound aminobarbital injection and antipyretic suppositories. If the diarrhea is more serious, montelukast can be given, along with drugs to regulate the intestinal flora, such as Saccharomyces boulardii, Clostridium typhimurium live dispersion, Lactobacillus bifidum triplex live tablets, and also drugs to protect the intestinal mucosa, such as rehabilitation new liquid, Metzolim, etc. If conventional drugs do not work to lower the temperature, stool tests and stool culture plus drug sensitivity tests can be performed to select sensitive drugs that are more specific to the infecting bacteria, which can better help to stop diarrhea and lower the temperature.