Sore throat and nose without air may be caused by upper respiratory tract infection, pharyngitis, allergic rhinitis and other factors. According to different causes can be treated by medication, such as cefixime, gargle furacilin liquid, roxithromycin capsule and so on. 1. Upper respiratory tract infection: Upper respiratory tract infection caused by pathogenic bacteria invading the body after the body’s immunity is reduced. The patient will have symptoms such as nasal disfluency, yellow nasal discharge, headache, sore throat, coughing up phlegm, accompanied by systemic symptoms such as fever, muscle weakness and so on. Cefixime, amoxicillin, roxithromycin, ribavirin and other drugs can be taken orally as prescribed by the doctor. 2. Laryngitis: Laryngitis caused by irregular lifestyle and decreased immunity. The patient will feel sore throat, foreign body sensation, burning or irritation, accompanied by symptoms such as the nose is not open to air. It can be treated and relieved through the use of furacilin solution, gargling with square borax solution, furosemide nasal drops, hydroxymetazoline nasal drops. 3. Allergic rhinitis: patients exposed to allergens lead to nasal mucosa stimulated by congestion, edema, easily caused by hypersensitivity reaction is manifested in the nose, runny nose, nasal itching, sore throat and other symptoms. It is recommended to take loratadine, cetirizine, montelukast sodium, blue scutellaria oral solution to control allergy and relieve sore throat symptoms. Sore throat and nose, need to actively seek medical attention, clear causes for targeted treatment, drugs need to follow the doctor’s instructions for rational application.