Normal urine protein quantitative is 150mg/24h or less, so urine protein quantitative 188mg/24h is not serious, but need to look for the cause of elevated urine protein, and according to the specific causes of treatment, mostly due to hypertension, diabetic nephropathy, glomerulonephritis, or physiological factors such as strenuous exercise and so on. 1. Hypertension: blood pressure can be controlled with angiotensin-converting enzyme inhibitors (ACEI), such as captopril; or angiotensin II receptor blockers (ARB), such as valsartan. Proteinuria 188mg/24h, this is in the early stage of the disease, the condition is relatively mild, after active and effective treatment, may return to normal. 2. Diabetic nephropathy: in addition to taking ACEI or ARB drugs, you also need to take drugs such as Carglitazone and Engelezine to control blood glucose, which can help to reduce proteinuria. 24-hour proteinuria 188mg, which is a mild increase, the condition is relatively mild, after active and effective treatment, it can be returned to normal in general. 3. Glomerulonephritis: ACEI or ARB drugs can be used in small doses, and hormone (e.g., prednisone acetate) treatment can be given if necessary. 24-hour proteinuria of 188mg is a small amount of proteinuria, and the condition is generally more stable, and even after treatment, the proteinuria can be returned to normal. 4. Physiological factors: such as strenuous exercise, nutcracker syndrome, eating a lot of meat, etc., generally after rest, weight gain, light diet can be returned to normal, so at this time the condition is also lighter. It is recommended that patients consult the hospital in a timely manner to identify the cause, follow the doctor’s instructions for treatment, do not self-medication.