An uncomfortable stomach with a cold back may be caused by gastric ulcer, gastroesophageal reflux, cholecystitis and other diseases, which require prompt medical attention to find out the cause of the disease. 1. Gastric ulcers: When gastric ulcers occur, the mucous membrane of the stomach will develop ulcerated surfaces, and gastric acid in the stomach will stimulate the ulcerated surfaces, so the symptoms of an upset stomach can occur. If gastric ulcer is more serious, it can lead to pain in the stomach, and when it is serious, it can also involve the back, and the back will be cold. 2. Gastroesophageal reflux (GER): GER is a disease in which the contents of the stomach and duodenum flow back into the esophagus, mouth, and lungs, causing discomfort. Due to excessive stomach acid, it can irritate the stomach, causing stomach discomfort, reflux, heartburn and other symptoms. When the reflux stimulates the esophagus, it can cause coldness behind the sternum, and in severe cases, it can cause severe pain. 3. Cholecystitis: due to gallstones, gallbladder duct inflammation and edema, roundworms and other causes of gallbladder duct obstruction, bile stagnation and concentration, stimulation of the gallbladder and thus cause inflammatory reaction. Inflammation of the gallbladder can involve the stomach and upset stomach occurs. When cholecystitis radiates to the back, it can lead to symptoms of coldness in the back. It is recommended that the patient go to the gastroenterology department of a regular hospital in time, complete the gastroscopy and other related examinations, identify the cause of the disease, and carry out targeted treatment under the guidance of the doctor.