Diastolic blood pressure higher than 110mmHg has reached the standard of grade 3 hypertension, which is very high, and severe elevation of diastolic blood pressure is prone to cause serious complications. Sudden increase to grade 3 hypertension or above may induce acute cerebrovascular diseases, such as hypertensive encephalopathy, severe blurring of vision, as well as arterial rupture due to the increase of blood pressure, leading to cerebral hemorrhage, and so on. Long-term persistent blood pressure above grade 3 is also likely to induce renal insufficiency, as well as ventricular hypertrophy due to elevated blood pressure, which may eventually lead to heart failure. If the diastolic blood pressure rises above 110mmHg, it is important to apply medication in a timely manner. Recommended is a combination of compounded preparations, such as Fodervin or valsartan amlodipine tablets.