Gray nail is a nail fungal disease produced by fungal infection of the nail, because often there will be nail deformation, hypertrophy, lime like changes, so it is customarily called gray nail. The treatment of gray nails starts with a clear understanding of the fungus inside the nail. There are various treatments for fungal removal, starting with oral and topical, oral medications such as itraconazole and terbinafine antifungal medications, and topical medications are also available, including ketoconazole, amorolfine cream and application. The course of treatment varies according to the growth time of the nail, nail turnover time is about 100 days, toenail turnover time is about 300 days, so the treatment of gray nails should have some patience, need a longer treatment process, gray nails can be eradicated after systematic antifungal treatment, as long as the patience to remove all the nail inside the fungus, will grow new perfect nails.