Creatinine is divided into blood creatinine and urine creatinine, the normal value standard of blood creatinine is: 44-133umol/L, urine creatinine is different between male and female, adult male 7.1~17.7mmol/24 hours urine, adult female 5.3~15.9mmol/24 hours urine. Blood creatinine is usually the amount of creatinine in a patient’s blood as a representation of kidney function. Blood creatinine belongs to the blood test, the normal value of blood creatinine is 44-133umol/L. When blood creatinine is more than 133umol/L, it means that the kidneys have been damaged, and there has been renal insufficiency and renal failure. Urinary creatinine is mainly from the blood after glomerular filtration of creatinine excreted with urine, urinary creatinine is rarely absorbed in the renal tubules, only a small amount is secreted into the urine. Urinary creatinine is a urine test, with normal values of 7.1 to 17.7 mmol/24-hour urine for adult men and 5.3 to 15.9 mmol/24-hour urine for adult women. Increased urinary creatinine may lead to uremia, complications, renal insufficiency and other hazards. If the patient has abnormal creatinine, it is recommended to go to the hospital in time, after clear examination, actively cooperate with the doctor for treatment.