There is no pattern to the timing of appendicitis pain. Acute appendicitis presents with epigastric pain that gradually shifts to the mid-abdomen and finally shifts and becomes confined to the lower right abdomen. Appendicitis most often presents with abdominal pain, characterized by metastatic right lower abdominal pain, but in many cases the pain is not typical, because there are different types of appendicitis and the pain manifestations vary. Abdominal pain varies from one type of appendicitis to another, for example, simple appendicitis manifests as mild vague pain; purulent appendicitis, mostly manifests as paroxysmal distension, and severe pain; gangrenous appendicitis manifests mainly as persistent severe abdominal pain. In perforated appendicitis, there may be a temporary reduction in abdominal pain due to a sudden decrease in pressure in the appendiceal cavity, followed by an increase in abdominal pain due to peritonitis. Chronic appendicitis may be atypical, with frequent symptoms such as lower right abdominal pain or vague discomfort. Symptoms alone cannot confirm the diagnosis of appendicitis. If appendicitis is considered to be the cause of the disease, it is important to consult a doctor in a timely manner, and ultrasound, blood tests and other tests to clarify the cause of appendicitis, which in principle should be treated with surgery in a timely manner.