The treatment of uterine mucinous smooth muscle sarcoma is mainly based on surgical treatment, supplemented by radiotherapy, chemotherapy and other treatments. Patients with mucinous smooth muscle sarcoma of the uterus who have small, more limited tumors and want to preserve their reproductive function can choose to have part of the uterus and cervix surgically removed under the guidance of their doctors. However, most patients have more extensive tumors and need to undergo total removal of the uterus and bilateral adnexa after diagnosis in order to achieve a complete cure. In addition, it is also necessary to cooperate with chemotherapy, and currently the commonly used method is doxorubicin, and radiotherapy such as pelvic irradiation can also be chosen. The treatment of uterine mucinous smooth muscle sarcoma is mainly based on surgery, but the specific treatment plan should be rationally selected under the guidance of professional doctors.