Fluconazole capsules are mainly used for the treatment of candidiasis, cryptococcosis, cryptococcal meningitis and coccidioidomycosis. Fluconazole is a triazole antifungal drug whose primary mechanism of action is to inhibit fungal ergosterol biosynthesis and thus come to inhibit fungal activity. It can be initiated before culture results and other laboratory studies are available; however, once results are available, antifungal therapy should be adjusted accordingly. Official guidelines should be consulted for the rational use of antifungal drugs. Common adverse reactions to fluconazole are nausea, headache, and rash; serious adverse reactions include hepatitis, cholestasis, and tip-twist tachycardia. When taking fluconazole, it should be noted that insufficient duration of treatment may lead to recurrence of infection. Fluconazole should be avoided in combination with the following drugs: 1. Coumarin anticoagulants: e.g. warfarin, the combination of which may lead to various bleeding events. 2. Others: also include phenytoin sodium, cyclosporine, rifampicin, theophylline, terfenadine, cisapride, etc. Fluconazole should be taken in strict accordance with medical advice.