Pityriasis rosea is an inflammatory, self-limiting papulosquamous skin disease with typical lesions of rose-colored blotches and macules covered with furfuraceous scales. The disease is self-limiting and treatment is aimed at reducing symptoms and shortening the course of the disease. It can be treated by topical medication, oral medication, physical therapy and other methods. 1. Topical medication: topical glycerite lotion or glucocorticoid such as Dinocaprolactone cream can be used locally to help reduce the skin lesions. 2. Oral medication: for those with obvious itching, antihistamine such as loratadine can be taken orally, and for those with serious condition or long course of disease, oral glucocorticoid such as prednisone can be taken for a short period of time in small dosage as appropriate. 3. Physical therapy: UVB irradiation can promote the lesions to subside and shorten the course of the disease. All the above drugs should be used according to the doctor’s advice. Pityriasis rosea is self-limiting, and the main purpose of treatment is to reduce the symptoms and shorten the course of the disease. It is recommended that the patient should consult the hospital in time, and carry out standardized treatment under the guidance of the doctor.