Adult m3 leukemia refers to acute promyelocytic leukemia, which is usually not passed from father to son. The cause of acute promyelocytic leukemia is not completely clear. It may be due to various factors such as genetics, environment and so on, which make the promyelocytic differentiation in bone marrow blocked, malignant clone and inhibit normal hematopoiesis, and widely invade various organs such as liver, spleen, lymph nodes and so on. Generally, the disease is not passed on to children. Ionizing radiation such as x-rays and γ-rays as well as long-term exposure to benzene and benzene-containing organic solvents, smokers, etc. can induce the development of the disease. There is also a relationship with heredity. People with genetic disorders such as Down’s syndrome and congenital immunoglobulin deficiency are more likely to develop acute promyelocytic leukemia due to genetic abnormalities. Adult acute promyelocytic leukemia is not a hereditary disease and is generally not inherited, but it is hereditary in nature.