A person who is negative for H. pylori but still has an upset stomach may be experiencing symptoms due to having gastritis, gastric ulcers, and other lesions of his or her own. Although H. pylori is an important cause of gastritis and gastric ulcer, some people with gastritis and gastric ulcers do not have H. pylori infection, so H. pylori is negative and can still have symptoms of an upset stomach, and this group of people will need to go through a gastroscopy in order to make a further diagnosis. After diagnosis through gastroscopy, you can take medication to treat the symptoms, if the symptoms continue to be unrelieved, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to determine the cause of the disease and targeted treatment, do not take medication, so as to avoid delays in the condition.