The HPV vaccine, also known as the human papillomavirus vaccine, is used to prevent cervical cancer from occurring.The HPV vaccine is currently available in the market as a 2-valent, 4-valent, and 9-valent vaccine, which are injected twice or thrice, respectively. The injection process often uses intramuscular injection, which will cause localized muscle pain at the injection site, but this pain is relatively mild and can be relieved soon after the injection. Like the hepatitis B vaccine and other vaccines, the pain does not last very long, so patients who receive the vaccine do not need to be overly nervous, as most people can tolerate the pain.