Shingles that does not come out generally refers to the tonic shingles. The herpes zoster is characterized by the appearance of erythema and papules without blisters, and can be treated with antiviral drugs and painkillers, which should be used in accordance with the doctor’s instructions. At present, the commonly used clinical therapeutic drugs for antiviral drugs, such as acyclovir, vasiclovir, etc., in order to effectively shorten the course of the disease, accelerate the healing of the rash. For patients causing pain, analgesics such as acetaminophen and tramadol can be used as appropriate. Postherpetic neuralgia can be treated with gabapentin or pregabalin. Neurotrophic drugs such as methylcobalamin tablets are also helpful in relieving nerve inflammation and nerve pain. Topical topical glycerite lotion and acyclovir cream can also be used to achieve anti-inflammatory and anti-viral effects. Shingles that does not come out should be promptly consulted and actively cooperate with the doctor to treat with medication.