Urine protein 300mg is mildly elevated. 24 hours urine protein normal value is below 150mg, if it is more than 150mg, it is elevated. Urine protein 300mg has exceeded 150mg, but it is not very high, it is mildly elevated. At this time, we should consider two situations: 1, physiological factors, check the 24-hour urine protein quantification before is not done strenuous exercise, such as running, swimming, etc.. If these factors are removed and the urine protein quantification returns to normal, no special treatment is needed. 2. pathological, most cases are caused by various nephritis, such as chronic nephritis and acute nephritis. At this time, you can use drugs to reduce urine protein, such as Huangkui capsule, Perindopril tablets, etc. In addition, the underlying disease should be treated, such as chronic nephritis needs to improve the microcirculation of the kidney, reduce urine protein, control blood pressure, etc., and acute nephritis needs to give anti-infection, diuretic and decongestant, control blood pressure and other treatment.