To investigate the clinical significance of the treatment of thoracolumbar fractures by transinfarct nailing with 6 nails and triple body fixation and selective single-segment bone grafting. METHODS: We retrospectively analyzed 32 patients with thoracolumbar fractures treated with transinfarctival 6-nail triple spine fixation and selective single-segment bone grafting from January 2006 to December 2008, who were followed up for more than 2 years, including 25 men and 7 women, aged 25-60 years, with an average age of 39.1 years. According to AO typing: 5 cases of A1.3 type, 17 cases of A3.1 type, 8 cases of A3.3 type, 1 case of C1.1 type, and 1 case of C1.3 type. The load score was 4 to 7, with an average of 5.8 points. Spinal cord nerve injuries were graded according to Frankel: 2 cases of grade A, 2 cases of grade B, 5 cases of grade C, 9 cases of grade D, and 14 cases of grade E. Their Cobb angle, anterior vertebral body margin height and degree of spinal canal occupancy were measured and compared preoperatively, postoperatively and at the final follow-up, while pain and labor capacity were evaluated using the Denis score. RESULTS: The cases in this group were followed up for 30 to 48 months, with a mean of 39.2 months. There was no loosening or fracture of the internal fixation, and the bone graft between the articular processes and the surface of the vertebral plate fused well in all cases except for three cases with floating wall bone scabs. The postoperative Cobb angle, the height of the anterior vertebral body and the occupancy of the vertebral canal were significantly improved compared with the preoperative period, but there was partial loss of spinal correction at the final follow-up compared with the postoperative period. In 25 cases of this group, CT scans at the final follow-up showed the presence of cavities of different sizes in the anterior and superior parts of the vertebral body. The spinal nerve function had recovered from grade I to II except for 2 cases with no change in grade A. Denis pain score P122 cases, P27 cases, and P33 cases. denis work status score W118 cases, W28 cases, W33 cases, and W5 3 cases. CONCLUSION: Although the treatment of thoracolumbar fractures by transinjured spine nailing with 6 nails and tri-vertebral body fixation and selective single-segment bone grafting can effectively restore the physiological curvature of the spine, the height of the anterior edge of the injured spine and the volume of the spinal canal, and there was no loosening or fracture of the internal fixation, and the low back pain was well relieved, it did not improve the hollow shell of the vertebral body and could not avoid the partial loss of correction.