Autoimmune hepatitis with mild abdominal edema and mildly enlarged spleen can be improved by general treatment, medication such as prednisone, and surgery. 1. General treatment: Due to the appearance of mild abdominal edema and mildly enlarged spleen, it is considered that there is still fluid retention, and it is necessary to strictly limit the intake of sodium and control the water in and out. At the same time, restrict protein intake. 2. Drug therapy: individualized treatment plan should be adopted according to the specific situation. Overall, it is to obtain histological remission and prevent liver fibrosis as well as liver failure, which can be treated with prednisone combined with azathioprine, or high-dose use of prednisone, with a longer course of treatment. 3. Surgery: If conservative treatment is ineffective and liver failure occurs, consider liver transplantation. Autoimmune hepatitis is a more serious type of hepatitis, it is recommended that once the diagnosis is made to consult a doctor in time, cooperate with the doctor to improve all kinds of examinations and carry out scientific and effective treatment.