Autoimmune hepatitis (AIH) is a chronic inflammatory necrotizing disease of the liver of unknown origin that can be triggered by a variety of causes, one of which is drugs. This drug-induced autoimmune hepatitis (DAIH) is a chronic inflammatory necrotizing disease of the liver of unknown origin. As early as the 1970s, Reynolds and Delchier et al. found that some AIH was associated with the laxative phentermine. However, for a long time, the occurrence of AIH was thought to be genetically related, and the triggering effect of drugs has been underappreciated, so there are fewer clinical reports. In recent years, there is a trend of increasing reports of DAIH in foreign literature year by year, but few reports in China. Early diagnosis of DAIH is very important for patients, and timely administration of appropriate immunosuppressive therapy can usually improve the patient’s condition and prevent or delay the onset of hepatic decompensation. Therefore, this article reviews DAIH in the hope that clinicians will have a better understanding of this particular type of liver damage.