1. General treatment Bed rest in the acute phase. Pay attention to the amount of fluid intake and output, nutrition and electrolyte balance. For those with gastrointestinal bleeding, if the abdominal pain is not severe and only the stool is positive for occult blood, a liquid diet can be used. Remove the causative factors Removal of infectious foci is the key to cure the disease, especially tonsillitis and other chronic infectious foci should be treated promptly. Those with parasitic infections should take anthelmintic drugs. Use cautiously or abstain from taking drugs and foods that may cause the disease. The first of these drugs is the antihistamine, which reduces the histamine response and capillary permeability and may reduce symptoms. 4. vitamin C and lutin enhance capillary resistance and reduce capillary permeability and fragility as an adjunctive therapy. 5. procaine Blockade therapy This therapy has the ability to regulate the central nervous system and inhibit allergic reactions. Usage: For negative skin test, add 150-300mg of procaine into 500ml of 5% glucose solution intravenously once a day for 7~l0d as a course of treatment. 6. Adrenocorticotropic hormone can inhibit antigenic antibody reaction and improve capillary permeability. It is effective in the improvement of soft tissue swelling, arthralgia and abdominal pain, as well as in nephrotic type and microscopic hematuria, but the efficacy is not sure for other types. The following conditions are indications for the use of hormones: (1) if there are serious gastrointestinal lesions, such as gastrointestinal bleeding, prednisone 1 to 2 mg/(kg・d) can be taken orally in divided doses, or dexamethasone or methylprednisolone can be given intravenously, and can be stopped after the symptoms are relieved; (2) if the manifestation is nephrotic syndrome, prednisone 1 to 2 mg/(kg・d) can be used for no less than 8 weeks; (3) for acute nephritis, methylprednisolone shock therapy can be used. Prednisolone shock therapy can be used for acute nephritis at the same dose as lupus nephritis. If hormone therapy is not effective, immunosuppressants can be added, such as cyclophosphamide. 7. gammaglobulin In severe cases, high-dose gammaglobulin shock therapy can be used. 7. immunosuppressants Immunosuppressants can be used when other methods for purpura kidney are not effective, and the combination with adrenal glucocorticoids often improves the efficacy. Commonly used drugs: cyclophosphamide 2-3mg/kg per day for several weeks to months, the nephrotic syndrome is more effective. Azathioprine 2-3mg/(kg・d). The dose should be adjusted according to the change of blood picture in the course of medication. 8. Hemostatic drugs Hemostatic 0.25-0.55g/time, intramuscular injection, 3/d, or Anlaucine 10mg/time, 3/d, intramuscular injection. When the bleeding is serious, the above two drugs are increased and changed to intravenous drip. Anti-platelet coagulation drugs Aspirin 3-5mg/(kg・d), orally once a day; Pansentine 3-5mg/(kg・d), in divided doses. 10. anticoagulation therapy The disease may have fibrinogen deposition, platelet deposition and intravascular coagulation, so in recent years there are reports of the use of heparin, the dose of heparin sodium The first of these is the use of a new type of heparin, which can be used for the treatment of the disease. This may be related to the removal of some of the immune complexes in the blood. In case of renal failure, dialysis can be used.12. Symptomatic treatment: ① abdominal pain: subcutaneous injection of atropine and 654-2 and other antispasmodics, also 0.1% epinephrine 0.5ml subcutaneously. ② swelling, low urine: diuretics and dehydrating agents are available. Renal insufficiency can be treated with hemodialysis, etc. ③Brain complications: high-dose glucocorticoids can be given intravenously, and dehydrating agents such as mannitol can be used for those with increased intracranial pressure. ④Gastrointestinal bleeding: in addition to intravenous haemostatic drugs, oral thrombin can be given, and blood transfusion can be given if there is a lot of bleeding.