The use of metronidazole suppositories should be noted for allergic reactions or some adverse reactions of the central nervous system in the course of the suppositories.1 If there are allergic reactions or some other adverse reactions, the medication should be stopped immediately.2 In addition, when treating vaginitis, the sexual partner should be treated at the same time.3. The use of metronidazole is prohibited for vaginitis.6 Metronidazole should also be used with caution in patients with liver and kidney insufficiency. Metronidazole suppositories are mainly used for the treatment of trichomoniasis and bacterial vaginosis and can be administered vaginally or rectally.