A choking and uncomfortable feeling inside the throat is considered to be caused by foreign body blockage, pharyngitis, reflux pharyngitis and other factors, which need to be treated with medication and surgery to address the cause of the disease. 1. Foreign body blockage; if the patient is stuck in the throat by fish splinter or sharp food when eating, there may be a choking and uncomfortable feeling inside the throat. If the foreign body can enter into the stomach by itself, no special treatment is usually needed. However, if the foreign body causes the patient to have difficulty in breathing, surgical treatment is needed to remove the foreign body with the help of a surgeon using instruments. 2. Pharyngitis; patients with pharyngitis will have dry, itchy eyes, difficulty in swallowing and other symptoms, manifested as a choking and uncomfortable feeling inside the throat. Patients follow the doctor’s instructions to use compound borax solution, furacilin solution, compound chlorhexidine gargle solution and other gargles, or oral vitamin A, vitamin C and other vitamin drugs. 3. Reflux pharyngolaryngitis; gastric contents reflux into the throat, there can be a kind of choking and uncomfortable feeling inside the throat. Patients follow the doctor’s instructions oral domperidone, mosapride, omeprazole and other drugs, if necessary, can take laparoscopic fundoplication. Once the patient has a kind of choking and uncomfortable feeling inside the throat, it is necessary to consult a doctor in time to clarify the diagnosis and standardize the use of drugs and treatment.