Ureteral stone 12x6mm patients need to cooperate with the doctor to remove it through surgical way, and can not be removed through medication. In the treatment of ureteral stones, treatment through drug lithotripsy applies to stones with a diameter of <0.6cm, a smooth surface, and no obvious obstruction below the stone. For patients with ureteral stones 12x6mm, they do not meet the criteria for drug lithotripsy, so patients can seek medical treatment through surgical procedures such as extracorporeal shock wave lithotripsy, transureteroscopic lithotripsy and lithotripsy. In addition to the above surgical methods, some patients can also be treated with percutaneous nephrostomy and drainage, and ureteral stent placement. After the surgical treatment, patients need to closely observe the urine output and vital signs, and when hematuria occurs, the doctor should be informed in time for treatment. If the condition permits, the patient should get out of bed as soon as possible after the operation to promote the discharge of small stones retained in the body. It is recommended that patients with ureteral stones 12x6mm go to a regular hospital in time, according to their own condition, cooperate with the doctor to choose the appropriate treatment plan, in order to achieve the ideal therapeutic effect.