Causes of midnight sleep sweating may be related to physiologic factors, tuberculosis, endocrine diseases, and hyperhidrosis. 1. Physiological factors: sleeping at night, the environment temperature is too high, the body’s metabolism will have the symptom of sweating in the sleep. 2. Tuberculosis: the most typical manifestations of tuberculosis are fatigue, low-grade fever, and night sweating (abnormal sweating after going to sleep, and sweating stops after waking up). Night sweating means sweating in the middle of the night while sleeping. 3. Endocrine diseases: patients with hyperthyroidism will sweat in the middle of the night due to the increase of basal metabolic rate, resulting in vigorous metabolism. 4. Hyperhidrosis: This is caused by autonomic dysfunction, in which case you will sweat a lot during the day. If you find the symptoms of midnight sweating, it is recommended to go to the regular hospital for examination, to clarify the cause of the disease, under the professional guidance of the doctor for treatment.