hbv-DNA refers to the hepatitis B virus nucleic acid test, which checks the amount of hepatitis B virus in the blood and is used to guide the need for hepatitis B antiviral drugs and to evaluate the efficacy of antiviral treatment afterwards. Currently, there are mainly high-sensitivity hepatitis B virus nucleic acid tests and general hepatitis B virus nucleic acid tests. The high-sensitivity hepatitis B virus nucleic acid test is more expensive and can only be done in large hospitals at a cost of about five hundred dollars. The normal hepatitis B virus nucleic acid test costs about one or two hundred dollars. The exact choice of test will depend on each person’s condition and financial situation.