The child coughs at two or three o’clock in the middle of the night, may be physiological cough; may also be the existence of allergic cough or even cough variant asthma. Generally speaking, the child in the middle of the night at two or three o’clock just occasionally cough a few times, and the child’s general condition is good, usually there is no abnormal performance, may be due to the indoor temperature is reduced, the inhaled air is too cold to stimulate the child’s throat, belong to the physiological cough, parents do not need to worry about too much. However, if the child has allergies, or there is the phenomenon of coughing after allergies, then we need to consider the cold air caused by allergic cough. Cough variant asthma is mainly manifested as a cough lasting more than 4 weeks and mainly dry cough, and no infection manifestations, the use of anti-infective drugs are also ineffective and other characteristics. Children coughing in the middle of the night two or three o’clock, there may be other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.