Bitter mouth in the morning may liver, biliary tract disease, gastrointestinal disease, for the cause of the disease to give liver protection, bile, regulating intestinal flora of drugs. 1. If the bitter mouth is caused by cholestatic liver disease, ursodeoxycholic acid can be taken orally. 2. If it is caused by Helicobacter pylori, anti-Helicobacter pylori drugs can be given, such as amoxicillin, clarithromycin, citrate secret tablets. If it is caused by gastrointestinal insufficiency, oral domperidone and mosapride can be given. 3. If it is bile reflux gastritis caused by oral gastric mucous membrane protective agent bismuth potassium citrate, promote gastrointestinal dynamics drug mosapride, acid inhibition drug omeprazole. In addition to medication, you should avoid spicy and stimulating food, do not eat greasy food, eat more easily digestible food, you can take oral probiotics to regulate intestinal flora.