In clinical practice, patients suffering from lumbar disc herniation can choose to be treated with sedative doses of mannitol solution, and the patient’s clinical symptoms will be relieved after 4-6 hours of sedative dosing. Mannitol solution is a dehydrating agent that can reduce the pressure in the lumbar spinal canal and reduce the patient’s nerve root edema through static dosing, which can relieve the irritation of the dural sac and nerve roots, resulting in a reduction of the patient’s clinical symptoms. When applying Mannitol Solution, it is best to use it properly under the guidance of a doctor, and choose different dosages according to the patient’s degree of illness, in order to better utilize the efficacy of Mannitol Solution and avoid accidents.