How long will febuxostat damage liver and kidney can not be generalized, due to differences in personal constitution, specific conditions, etc., patients taking febuxostat how long will damage liver and kidney or whether it will damage liver and kidney can not be given the exact time. Febuxostat reduces the concentration of uric acid in the blood by inhibiting uric acid synthesis, and the common adverse effects of this drug include liver function abnormalities, nausea, arthralgia and skin rash. Experimental data show that the incidence of liver function abnormalities in patients taking different doses of Febuxostat during the 6-12 month treatment period is different. Therefore, due to the differences in patients’ physical condition and specific medical conditions, it is not possible to give an exact time for how long it will take to damage the liver and kidneys and whether liver and kidney function abnormalities will occur. In addition, according to the relevant toxicology data, Febuxostat has not been shown to be genotoxic or toxic to reproduction. It is contraindicated in patients who are hypersensitive to the drug or who are receiving azathioprine or mercaptopurine therapy. Note that patients with severe renal impairment should be cautious, gouty arthritis should not be used in the acute stage of patients, during the use of the drug closely monitor the deterioration of existing cardiovascular disease or the symptoms of new cardiovascular disease. Drugs need to be used under the guidance of a physician, it is recommended that patients who need to take febuxostat to the rheumatology and immunology department of the regular hospital for consultation.