Taking too much nifedipine extended-release tablets can be immediately given gastric lavage, if necessary, give small bowel enema, the use of dopamine and other drugs for treatment. Nifedipine extended-release tablets belong to the calcium channel blocker, after taking it can reduce the extracellular calcium ions into the vascular smooth muscle cells, reduce the contraction response of the resistance blood vessels, so as to play a role in lowering blood pressure. It is mainly used in the treatment of angina pectoris, hypertension and other diseases. If the drug is not taken in accordance with the doctor’s instructions, and after taking an overdose may occur serious nifedipine poisoning, which can cause coma, blood pressure drop, tachycardia, hyperglycemia, cardiogenic shock and other discomforts. The first thing that should be taken into account is the elimination of the active ingredient, as well as the restoration of stabilization of the cardiovascular state. Therefore, it is necessary to immediately carry out gastric lavage therapy under the supervision of a doctor, and, if necessary, give an enema of the small intestine, which is able to prevent the absorption of active components. However, hemodialysis is not recommended, as it is of little significance. Treatment with sympathomimetic vasoconstrictors such as dopamine and norepinephrine can also be chosen if necessary. If an overdose occurs during treatment with nifedipine extended-release tablets without following the doctor’s instructions, it is recommended to stop the medication immediately and seek medical treatment in time to avoid delaying the best treatment time.