A high total bile acid of 70umol/L is considered to be caused by physiological or pathological factors, physiological factors such as eating, staying up late, excessive stress, etc. Pathological factors are commonly found in hepatobiliary diseases, such as acute hepatitis, bile duct obstruction, etc. It is recommended to consult a specialist. Total bile acid can be measured on an empty stomach or 2 hours after a meal, with a normal value of 0-10 umol/L. It is suitable for the diagnosis of people who are suspected of having liver disease but other biochemical indicators are normal or mildly abnormal. 1. Physiological factors: serum total bile acid may rise transiently after eating and then fall to normal, which is a normal physiological phenomenon and does not need treatment; or total bile acid may rise due to excessive stress or staying up all night, etc., which can be restored to normal by improving lifestyle and relieving stress. 2. Pathological factors: it can be seen in hepatocellular damage, such as acute hepatitis, cirrhosis, hepatocellular carcinoma, etc., biliary obstruction, such as intra-hepatic and extra-hepatic bile duct obstruction, portal shunt, etc., which needs timely treatment. When the total bile acid is elevated, it is recommended to clarify the cause in time, and the pathological factors need to be diagnosed and treated in time.