Elevated globulin after total excision of nail cancer may be caused by inflammation, recurrence of nail cancer after surgery, further examination is needed to clarify the cause of the disease and timely symptomatic treatment. Elevated globulin after total excision of nail cancer may be caused by inflammation, most of which is caused by bacterial infection in surgical incision site, untimely changing of medicine, which leads to wound inflammation, and elevated globulin found in blood test, which can be treated with drugs such as cefuroxime, cefradine and so on. Elevated globulin after total excision of thyroid cancer is caused by recurrence of thyroid cancer after surgery. Thyroglobulin is an important sign of recurrence of thyroid cancer after surgery, if it is found to be elevated, which suggests recurrence of thyroid cancer, further checkups, such as CT, ultrasound and so on, are needed to confirm the diagnosis and carry out symptomatic treatment. Therefore, patients with elevated globulin after total excision of thyroid cancer should go to the hospital as soon as possible to confirm the diagnosis and actively cooperate with doctors for symptomatic treatment after confirmation.