Pityriasis rosea is an inflammatory, self-limiting papular-scaly skin disease with typical lesions of rose-colored blotches and macules covered with furfuraceous scales. Recurrent flare-ups of pityriasis rosea may be caused by a decrease in the body’s resistance. The etiology of pityriasis rosea is not very clear at present and is now thought to be related to viral infections. The cellular immune response may be involved in the development of the disease, possibly due to the fact that when the body’s resistance is lowered, the virus attacks the patient’s body, leading to recurrent flare-ups of pityriasis rosea. The disease is self-limiting, and the course of the disease is usually 6 to 8 weeks, and there are also cases that do not heal for several months or even years. Topical glycerite lotion or glucocorticoids can be used externally. If the itching is obvious, oral antihistamine can be taken, and if the condition is serious or the duration of the disease is long, oral glucocorticoids can be taken for a short period of time in small doses as appropriate. Irradiation of UVB can promote skin lesions subside, shorten the course of the disease. There may be other reasons for the recurrence of pityriasis rosea, it is recommended to go to the regular hospital for examination in a timely manner, and standardized treatment under the guidance of professional doctors.