If chemotherapy is needed, it should be stratified according to the risk of recurrence, and then choose what kind of chemotherapy regimen to use, as follows: 1) if it is early neoadjuvant chemotherapy, do 6-8 cycles; 2) if it is post-operative adjuvant chemotherapy, patients with high risk of recurrence, generally do 8 cycles of chemotherapy, and there is an intensive regimen of 12 cycles, and the number of cycles varies according to the regimen; 3) if the risk of recurrence is low, but chemotherapy is needed, generally do 4 cycles, depending on the arrangement of the doctor in charge.