Some patients find out about tubal fluid before IVF and may wonder if it is serious, if they should be treated first, and how to treat it. Today we will learn about the impact of tubal fluid on assisted reproduction and treatment options. Tubal infertility accounts for 30%-40% of female infertility, while infertility caused by hydrosalpinx accounts for another 10%-30% of tubal factors. The existence of tubal hydrocele reduces 50% of the implantation rate and clinical pregnancy rate, and increases the risk of spontaneous abortion by one times, and raises the incidence of ectopic pregnancy, and the treatment of tubal hydrocele before IVF has reached the consensus of experts at home and abroad. Clinical manifestations 1, dysmenorrhea: the closer to the menstrual period, the more serious the pain, until the onset of menstruation can be relieved. Irregular menstruation: excessive menstrual flow or obvious increase in the number of menstrual periods. 3.Infertility: causing tubal obstruction, leading to infertility. 4.Ectopic pregnancy. 5.May have increased vaginal discharge, watery leukorrhea, etc. Examination 1.Tubalography: the most reliable method to confirm the diagnosis. 2.Ultrasonic diagnosis 3.Laparoscopy Influence mechanism 1.Mechanical flushing: the inflow of fluid into the uterine cavity can affect the contact between the embryo and the endometrium, and also flush away the embryo that has not yet been implanted from the implantation site. 2. Embryotoxicity: the fluid contains tissue debris, lymphocytes or microorganisms, and toxic molecules, which may have toxic effects on the embryo and inhibit embryonic development when the fluid contacts the embryo. 3.Impaired endometrial tolerance: Cumulus reduces the tolerance of the endometrium by altering the expression of endometrial tolerance factors and decreases the rate of implantation. On the other hand, infection, the main cause of hydrops, can cause endometrial and subendometrial blood flow reduction. 4, inhibit ovarian function: tubal hydrosalpinx can compress ovarian blood vessels, reduce its blood supply, inhibit ovarian function. 5, sperm fertilization ability is impaired: tubal hydrocele can make the sperm vitality and acrosome reaction ability decreased, so for the time being no plan to IVF, regular ovulation but infertile patients with tubal hydrocele should be actively dealt with hydrocele. Treatment 1, Tubectomy: It is the only surgical procedure that has been studied in randomized controlled trials with enough samples, and there is enough evidence to recommend this treatment before IVF. Unilateral salpingo-oophorectomy has a high rate of spontaneous pregnancy. Laparoscopic surgery is often chosen to “clean up” the fallopian tubes and abdominal cavity. 2, tubal ligation: for serious adhesions, the difficulty of excision, proximal tubal ligation is a good choice, blocking the flow of fluid to the uterine cavity. However, because the fluid is not treated, the fluid may be mistaken for follicles and punctured during egg collection. 3.Tubal Hydrocele Aspiration: It reduces the pressure in the fallopian tube and prevents the flow of the fluid to the embryo and also blocks its embryotoxic effect. 4.Tubal embolization: micro-spring is fully delivered into the mesosalpinx and isthmus of the fallopian tube to block the pathway. This is a relatively new treatment method, and its effectiveness has not been confirmed by large sample studies. 5, antibiotics: the main cause of tubal is chronic inflammation, the above program can be combined with antibiotics to fight infection. Hydrosalpinx has a significant adverse effect on the outcome of assisted reproduction by poisoning the “seed” (embryo), destroying the “soil” (endometrium), preventing contact between the two, and reducing the source of “fertilizer” (ovaries). This has a significant adverse effect on the outcome of assisted reproduction. In patients who are ready to conceive, aggressive management is recommended in clinical practice in cases of ultrasound-visible hydrosalpinx, with prophylactic salpingo-oophorectomy being the preferred option.