Thyroid puncture results of atypical lesions of unknown significance are generally treated with options such as repeat fine-needle aspiration biopsy, genetic testing, or surgical resection.
Atypical cells of unknown significance on thyroid puncture indicate that there are atypical features of the cells or structure of the tissue, which are different from normal tissue manifestations and cannot be classified as follicular or malignant tumors, with some degree of malignant risk.
Re-experimentation with fine needle aspiration biopsy can reduce the error to further clarify the diagnosis. Genetic testing can assist in the assessment of the benignity and malignancy of thyroid lesions, or direct surgical resection can be performed, with intraoperative pathology to clarify the diagnosis to guide the scope of surgical resection.
Patients are advised to consult a specialist for further examination and treatment.