If the pain in the chest area is induced by exertion, the most important thing to pay attention to is coronary artery disease. Angina pectoris in coronary artery disease is induced by exertional activity, and the pain in the chest area can be manifested as a pressure-like or tightening sensation, sometimes radiating to the left upper limb, back, neck, etc. Patients with risk factors such as obesity, smoking, hypertension, hyperlipidemia, men over 45 years of age, or women after menopause should pay more attention to this condition. If the patient’s ischemic changes cannot be detected after repeatedly experiencing similar conditions and the pain lasts only for a few minutes, the patient should undergo an ECG or even a coronary CTA to further evaluate the condition and prevent any missed diagnosis of coronary artery disease.