Does chromosome 47 affect fertility?

Chromosome 47 affects fertility.
The normal human body is 23 pairs of 46 chromosomes, when there are 47 chromosomes, both the existence of chromosomal abnormalities of the disease, common including 13-trisomy, 18-trisomy, 21-trisomy, sex chromosome syndrome, etc..
These chromosomal disorders are usually associated with reproductive dysfunction, abnormal mental development, and a variety of physical defects, and may be directly passed on to the offspring.
Therefore, in order to meet the fertility needs of this group of people, it is necessary to improve the chromosome examination of both husband and wife to clarify the type of chromosomal diseases. If there is no obvious structural abnormality, it is possible to select healthy embryos for transplantation and birth through three-generation IVF. However, if there are obvious structural abnormalities, it is not recommended to have children.