Numbness of the hands and feet during recovery from optic neuromyelitis optica may be a symptom caused by the disease itself, or it may be caused by a new lesion. 1. Normal symptoms: If numbness persists during recovery, it is generally considered a normal clinical symptom. Optic neuromyelitis optica tends to be more likely to cause central nervous system and spinal cord lesions, causing numbness in the hands and feet. 2. New lesions: If the numbness in the hands and feet has disappeared after treatment, and then suddenly appears again during the recovery period, it is necessary to consider that it may be caused by new lesions, and it is necessary to go to the regular hospital for further examination and treatment. In addition, during the recovery of optic neuromyelitis optica complicating other diseases, such as cerebral infarction, peripheral neuritis, etc., may also appear numbness of hands and feet. It is recommended that the patient consult a doctor in time to clarify the cause under the doctor’s guidance and carry out targeted treatment.