Acne belongs to the category of “pimples” in Chinese medicine, mostly due to wind-heat in the lungs, damp-heat in the stomach and intestines, as well as phlegm-dampness internal obstruction (phlegm and dampness blocking the body’s internal organs and meridians), and moxibustion can aggravate such conditions, followed by acne. Moxibustion has the effect of warming the meridians and dispersing cold (warming the meridians and eliminating cold), eliminating blood stasis and dispersing knots, and supporting the yang fixed off (by way of replenishing the yang qi to treat prolapsed type of disease), and so on, and its nature is warm and dry and can be transformed into heat and hurt the yin, and if it is moxibustion is too much, too long, for the lungs of the wind-heaters and the gastrointestinal dampness and heaters can be aggravated by the heat potential for phlegm and dampness obstruction that may lead to the transformation of the dampness and heat. Therefore, the appearance of acne on the face after moxibustion may be due to moxibustion aggravates the causative disease mechanism that leads to acne. Moxibustion operation needs to be operated by a professional doctor, do not apply moxibustion without authorization to avoid the risk. It is recommended that the person who has acne after moxibustion should consult a professional doctor in time for the identification of medication and treatment, so as not to delay the condition.