Cranial repair is a common brain surgery procedure to repair the skull for cranial defects caused by traumatic brain injury. Patients with cranial defects often have a heavy burden of insecurity and can cause syndromes such as headache, dizziness, and fear of vibration. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. In order to restore the cranial cavity confinement, keep the physiological intracranial pressure stable and reduce the cranial defect syndrome. In order to restore the cranial cavity, keep the physiological intracranial pressure stable, and reduce the cranial defect syndrome, cranial repair should be performed for cranial defects with a diameter of 3 cm or more, without muscle coverage and without contraindications. PEEK is an aromatic semi-polymer with low density, insensitive to temperature, and high tissue stability, which allows it to be sterilized at high temperatures or under radiation without deformation. It is radiopaque and has no effect on CT and MRI results. In addition, the material can be 3D printed or CAD/CAM’d to create cosmetically pleasing implants. In general, cranial defects can be repaired after the age of 3 years, and cranial growth is relatively slow after the age of 3 years. It can improve brain tissue development and promote neurological recovery. At present, we are experienced in using PEEK material for skull repair surgery, and our surgical skills are so skilled that patients can recover the skull shape and beauty after surgery. It is recommended that patients go to regular hospitals to take appropriate repair materials for repair as soon as possible to restore health.