Nail seam itching is a very common phenomenon in the clinic, can cause nail seam itching for a number of reasons, the most common reasons in daily life are the following: 1, infection: bacterial and fungal infections will appear localized itching of the skin. The skin will appear erythema, blisters, and accompanied by oozing, you can go to the hospital to do fungal immunofluorescence test, diagnosis of fungal infection in time after antifungal treatment.2, contact dermatitis: hands are very easy to contact with the outside world, if you want to contact with laundry detergent, laundry detergent or chemicals, there will be localized itching sensation.3, eczema dermatitis: hands of patients with eczema prone to itchiness, hypersensitivity reaction will occur.4, seasonal dermatitis: in the season of seasonal dermatitis, the skin will appear itchy, but the skin is also very itchy. Seasonal dermatitis: At the change of seasons, especially in the fall and winter and spring and winter seasons, the skin will be dry and peeling, accompanied by itching sensation.