Tacrolimus ointment is very itchy after application, if it is a phenomenon of irritation, then it can be suspended for 1 to 2 days or reduce the number of times the drug is used, and after a few days of gradual adaptation can continue to use. If it is an allergy to the medication or the ingredients of the cream, you need to stop using this medicine. Some local symptoms such as burning sensation and itching of the skin may occur with the use of tacrolimus ointment. Most of the itching symptoms are common in the first few days of using the drug and will disappear as the affected skin improves, and this condition does not require any special treatment. Tacrolimus ointment may also have some adverse reactions, such as allergic reactions, also manifested as itching, in this case you should have to stop using the drug, wash the drug off with water, you can take oral anti-allergy drugs, such as loratadine, cetirizine and so on. Tacrolimus ointment is very itchy after application, you should have to choose the appropriate treatment under the guidance of the doctor. This drug has more adverse reactions, and should be used in strict compliance with the doctor’s instructions, not blindly used on their own. It is contraindicated for those who are allergic to this drug.