Patients with pain in the palm area, the clinical should consider the following diseases: 1, trauma: trauma to the skin of the palm area, such as ligature, contusion, etc., can lead to local skin inflammatory disease, manifested as local skin pain; 2, arthritis or tenosynovitis: can lead to localized pain; 3, neuritis: such as herpes zoster occurring in the upper limb area, can lead to viral neuritis, manifested as skin pain in the palm; 4, Cervical spondylosis: such as cervical spondylotic hyperplasia, can compress the nerve and lead to palmar skin pain; 5, cardiovascular and cerebrovascular lesions: can lead to radiating palmar area of skin pain. Patients with palmar pain should go to the emergency department or dermatology department of regular hospitals in time, with relevant auxiliary examinations, to clarify the causes of palmar pain and related diseases, and give correct and timely treatment.