Gastrointestinal reactions are one of the most common side effects after chemotherapy. For patients, it is mainly manifested as nausea and vomiting, loss of appetite, etc. There are currently better clinical treatments for gastrointestinal reactions. The application of antiemetic drugs is usually given to patients before chemotherapy. In the early stage, the main application is gastrofacial, also called metoclopramide, which can reduce the gastrointestinal reaction by promoting the emptying of the gastrointestinal tract, but its effect is relatively weak. In recent years, 5-hydroxytryptamine receptor inhibitors are the most commonly used antiemetic drugs in clinical practice, which have a better antiemetic effect compared to metoclopramide. The main clinical applications include granisetron, ondansetron and palonosetron, which are more commonly used drugs. In recent years, there are newer drugs called aripitant, which has a better antiemetic effect than 5-hydroxytryptamine inhibitors and is mainly available in oral dosage form. These can be effective in controlling, delaying or reducing gastrointestinal reactions after chemotherapy. In addition to medication, patients are generally advised to pay attention to their diet during chemotherapy, mainly by eating a light diet, reducing grease and reducing the stimulation of food on gastrointestinal reactions. In this way, the control of gastrointestinal reactions will also be helpful. In addition, there are some patients, gastrointestinal reactions are more obvious, especially nausea, vomiting or induced nausea and vomiting after eating is more common or more serious. At this time, it is generally recommended that patients should fast for a short period of time, give rehydration treatment, give repair to the gastrointestinal system, and then gradually return from a light diet to or transition to a normal diet after the symptoms have been relieved. In this way, the symptoms will also be greatly helped.