Bilateral mastoiditis usually does not heal on its own. Most of the mastoiditis is caused by middle ear infections. If the body’s immunity and active treatment are not used without medication, the disease usually does not heal on its own, and even progresses, making it difficult to treat. Mastoiditis is a purulent inflammation of the mucous-osteum of the mastoid air cavity, especially the mastoid bone. There are acute mastoiditis and chronic mastoiditis. It is mostly associated with acute suppurative otitis media and chronic suppurative otitis media. Bilateral acute mastoiditis before the onset of most of the acute suppurative otitis media, acute suppurative otitis media if you do not use a sufficient amount of cephalosporin or penicillin and other antibiotics to treat, only by the body’s immunity, the inflammation and infection is generally unable to effectively subside, so the majority of bilateral acute mastoiditis can not be cured by itself. Chronic mastoiditis is associated with chronic suppurative otitis media, which is not only located in the tympanic cavity, but also often invades the sinus, mastoid and eustachian tube. Chronic suppurative otitis media often requires surgery if conservative treatment is not effective. If the mastoiditis is not treated aggressively, the inflammation may spread, resulting in extracranial and intracranial complications. It can be seen that when there is acute and chronic suppurative otitis media, it is recommended to actively standardize the treatment.