Acute inferior wall myocardial infarction is one of the most common types of clinical myocardial infarction. If the diagnosis of acute inferior wall myocardial infarction is confirmed by electrocardiogram, it is recommended to administer dual anti-drug such as aspirin and clopidogrel 300 mg each orally as soon as possible, followed by aggressive symptomatic treatment such as PCI and thrombolysis within the time window. If the patient’s vital signs are unstable, active basic vital signs treatment is required. Under the premise of ensuring the basic vital signs are stable, the next step of treatment such as stenting or thrombolysis should be considered. Inferior wall myocardial infarction tends to have low blood pressure and requires careful use of nitroglycerin.